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Ethyl alcohol
Ethyl alcohol acts as a protoplasmic poison and denaturant that kills cancer cells through protein denaturation and cellular damage.
Ethyl alcohol acts as a protoplasmic poison and denaturant that kills cancer cells through protein denaturation and cellular damage. Used for Hepatocellular carcinoma (percutaneous ethanol injection), Tumor ablation (direct injection).
At a glance
| Generic name | Ethyl alcohol |
|---|---|
| Also known as | Chemical neuolysis |
| Sponsor | South Egypt Cancer Institute |
| Drug class | Cytotoxic agent / Sclerosing agent |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | FDA-approved |
Mechanism of action
Ethanol denatures proteins and disrupts cellular membranes, leading to cell death. In oncology contexts, it has been used as an ablative agent for direct injection into tumors or as a sclerosing agent. The mechanism is non-selective cytotoxicity rather than targeted therapy.
Approved indications
- Hepatocellular carcinoma (percutaneous ethanol injection)
- Tumor ablation (direct injection)
Common side effects
- Pain at injection site
- Hepatotoxicity
- Systemic toxicity from absorption
- Fever
Key clinical trials
- Characterization Imaging Instruments in Alcoholics and Non-Alcoholics
- A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder (PHASE2)
- Effect of Alcohol Sclerotherapy on Pelvic Pain and Quality of Life in Women With Ovarian Endometriosis (NA)
- Tirzepatide in MetALD (PHASE2)
- NIAAA Natural History Protocol
- Hepatic Lipid Metabolism-Alcohol Use Disorder
- Assessment of Non-Invasive Testing in Major Liver-Related Outcomes
- Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD) (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Ethyl alcohol CI brief — competitive landscape report
- Ethyl alcohol updates RSS · CI watch RSS
- South Egypt Cancer Institute portfolio CI