Last reviewed · How we verify
ETHAMBUTOL HYDROCHLORIDE
At a glance
| Generic name | ETHAMBUTOL HYDROCHLORIDE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 1967 |
Approved indications
Common side effects
- Decreased visual acuity
- Nausea
- Vomiting
- Anorexia
- Gastrointestinal upset
- Abdominal pain
- Headache
- Dizziness
- Fever
- Malaise
- Pruritus
- Joint pain
Serious adverse events
- Irreversible blindness
- Optic neuritis
- Retrobulbar neuritis
- Peripheral neuritis
- Anaphylactic/anaphylactoid reaction
- Liver toxicities including fatalities
- Thrombocytopenia
- Leucopenia
- Neutropenia
- Mental confusion and disorientation
Key clinical trials
- Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (PHASE2)
- Shortened Regimen for Drug-susceptible TB in Children (PHASE3)
- Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial (PHASE2)
- Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (PHASE2)
- Treatment of Tuberculosis Multidrug Resistance Treatment of Tuberculosis Multidrug Resistance
- AIPH-TB: AI-Optimised Pyrazinamide-Hydroxychloroquine vs Standard RIPE for Drug-Sensitive Pulmonary Tuberculosis - A Phase II RCT (PHASE2)
- Phase 2a Trial of Alpibectir Plus Ethionamide for Tuberculosis Meningitis (PHASE2)
- Digitally Facilitated, Integrated Community and Facility-Based Interventions: The HEART-TB Trial Protocol (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ETHAMBUTOL HYDROCHLORIDE CI brief — competitive landscape report
- ETHAMBUTOL HYDROCHLORIDE updates RSS · CI watch RSS