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estradiol plus MPA
estradiol plus MPA is a Small molecule drug developed by Peking Union Medical College Hospital. It is currently FDA-approved.
Estradiol, an estrogen receptor alpha agonist, is used in combination with medroxyprogesterone acetate (MPA) to treat conditions such as estrogen deficiency, cardiovascular disease, and endothelial dysfunction. This combination is typically administered in a dosage of 0.625 mg of conjugated equine estrogen plus 2.5 mg of MPA.
At a glance
| Generic name | estradiol plus MPA |
|---|---|
| Sponsor | Peking Union Medical College Hospital |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015) (PHASE2)
- Intrauterine Stent Placement Following Hysteroscopic Septum Resection (NA)
- Estrogen Receptor Beta and Mood (PHASE2)
- Efficacy and Safety of Huanjingjian Decoction in Women With Premature Ovarian Insufficiency (NA)
- Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women (PHASE2)
- A Study Run At Multiple Study Sites to Test Whether the SAMANTA Questionnaire That is Used to Diagnose Heavy Menstrual Bleeding (HMB), Can Also Be Used to Assess Changes of Severity of HMB in Women with HMB Who Are Treated During 12 Months with a Chronic Hormonal Treatment
- Euploid Rate of Blastocyst Derived From PPOS VS Antagonist Protocol (NA)
- Hormone Replacement Therapy for Hot Flashes and/or Vaginal Symptoms in Postmenopausal Women Receiving Tamoxifen for Breast Cancer (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- estradiol plus MPA CI brief — competitive landscape report
- estradiol plus MPA updates RSS · CI watch RSS
- Peking Union Medical College Hospital portfolio CI
Frequently asked questions about estradiol plus MPA
What is estradiol plus MPA?
Who makes estradiol plus MPA?
What development phase is estradiol plus MPA in?
Related
- Manufacturer: Peking Union Medical College Hospital — full pipeline
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing