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ESP Catheter
The ESP Catheter is an electrosurgical ablation device that uses radiofrequency energy to create lesions in cardiac tissue for arrhythmia treatment.
The ESP Catheter is an electrosurgical ablation device that uses radiofrequency energy to create lesions in cardiac tissue for arrhythmia treatment. Used for Atrial fibrillation ablation via pulmonary vein isolation.
At a glance
| Generic name | ESP Catheter |
|---|---|
| Sponsor | University of Minnesota |
| Drug class | Cardiac ablation catheter |
| Modality | Small molecule |
| Therapeutic area | Cardiology |
| Phase | FDA-approved |
Mechanism of action
The ESP (Electrosurgical Pulmonary vein isolation) Catheter delivers controlled radiofrequency energy through its tip to ablate abnormal cardiac tissue, particularly in the pulmonary veins and left atrium. This creates scar tissue that blocks the electrical signals responsible for atrial fibrillation, restoring normal heart rhythm. The device is designed to enable precise, efficient pulmonary vein isolation during catheter ablation procedures.
Approved indications
- Atrial fibrillation ablation via pulmonary vein isolation
Common side effects
- Pulmonary vein stenosis
- Cardiac tamponade
- Esophageal injury
- Thromboembolic events
Key clinical trials
- Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH (PHASE2, PHASE3)
- Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature
- Thoracic Epidural Analgesia With Bilateral Erector Spinae Plane Block in Radical Cystectomy Surgery (NA)
- Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery (NA)
- Cryo Rib Fracture Study (PHASE4)
- Ventricular Tachycardia Ablation and Myocardial Scar Characterization With Magnetic Resonance (PHASE4)
- Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery
- EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- ESP Catheter CI brief — competitive landscape report
- ESP Catheter updates RSS · CI watch RSS
- University of Minnesota portfolio CI