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ESL Tutti-Frutti taste

Bial - Portela C S.A. · Phase 2 active Small molecule

ESL works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4).

ESL works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). Used for Type 2 diabetes.

At a glance

Generic nameESL Tutti-Frutti taste
Also known asEslicarbazepine acetate (ESL)
SponsorBial - Portela C S.A.
Drug classDPP-4 inhibitor
TargetDPP-4
ModalitySmall molecule
Therapeutic areaDiabetes
PhasePhase 2

Mechanism of action

This inhibition increases the levels of incretin hormones, which in turn increases insulin release in response to meals and decreases glucagon levels in the circulation during the postprandial period. This results in lowering of glucose levels.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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