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Drisdol (ERGOCALCIFEROL)

Esjay Pharma · FDA-approved approved Small molecule Quality 42/100

Drisdol (Ergocalciferol) is a provitamin D2 compound developed by Sanofi Aventis US and currently owned by Esjay Pharma. It targets the 25-hydroxyvitamin D-1 alpha hydroxylase enzyme and is used to treat various bone disorders, including rickets, osteoporosis, and hypocalcemia. Drisdol is a small molecule modality that has been FDA-approved since 1941 and is now available as a generic medication. It is used to treat a range of conditions, including familial x-linked hypophosphatemic vitamin D refractory rickets, glucocorticoid-induced osteoporosis, and hyperparathyroidism secondary to chronic renal failure. Drisdol is off-patent and has multiple generic manufacturers.

At a glance

Generic nameERGOCALCIFEROL
SponsorEsjay Pharma
Drug classProvitamin D2 Compound [EPC]
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
ModalitySmall molecule
Therapeutic areaMetabolic
PhaseFDA-approved
First approval1941

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
FDA labelMechanism, indications, dosing, boxed warnings, drug interactions
ClinicalTrials.govTrial enrolment, design, endpoints, results

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