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EQW plus DAPA

Woman's · Phase 3 active Small molecule

EQW (semaglutide) is a GLP-1 receptor agonist combined with DAPA (dapagliflozin), an SGLT2 inhibitor, to provide dual glucose-lowering effects through incretin mimicry and urinary glucose excretion.

EQW (semaglutide) is a GLP-1 receptor agonist combined with DAPA (dapagliflozin), an SGLT2 inhibitor, to provide dual glucose-lowering effects through incretin mimicry and urinary glucose excretion. Used for Type 2 diabetes mellitus.

At a glance

Generic nameEQW plus DAPA
Also known asBydureon plus Farxiga, Long acting GLP1 agonist plus SGLT2 inhibitor
SponsorWoman's
Drug classGLP-1 receptor agonist + SGLT2 inhibitor combination
TargetGLP-1 receptor; SGLT2
ModalitySmall molecule
Therapeutic areaDiabetes
PhasePhase 3

Mechanism of action

Semaglutide activates GLP-1 receptors to enhance insulin secretion, suppress glucagon, and slow gastric emptying. Dapagliflozin inhibits sodium-glucose cotransporter 2 in the kidney to increase urinary glucose excretion. Together, they provide complementary mechanisms for glycemic control and cardiovascular/renal benefits in type 2 diabetes.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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