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Epirubicin with a Taxane

Pfizer · Phase 3 active Small molecule

Epirubicin with a Taxane is a Chemotherapy combination (anthracycline + microtubule stabilizer) Small molecule drug developed by Pfizer. It is currently in Phase 3 development for Breast cancer (early-stage and metastatic), Gastric cancer, Ovarian cancer. Also known as: Epirubicin, ellence,.

Epirubicin and taxanes work together as chemotherapy agents that damage cancer cell DNA and disrupt microtubule formation, respectively, to kill rapidly dividing tumor cells.

Epirubicin and taxanes work together as chemotherapy agents that damage cancer cell DNA and disrupt microtubule formation, respectively, to kill rapidly dividing tumor cells. Used for Breast cancer (early-stage and metastatic), Gastric cancer, Ovarian cancer.

At a glance

Generic nameEpirubicin with a Taxane
Also known asEpirubicin, ellence,
SponsorPfizer
Drug classChemotherapy combination (anthracycline + microtubule stabilizer)
TargetDNA (epirubicin); β-tubulin/microtubules (taxane)
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 3

Mechanism of action

Epirubicin is an anthracycline that intercalates into DNA and generates reactive oxygen species, causing DNA damage and cell death. Taxanes (paclitaxel or docetaxel) stabilize microtubules and prevent their disassembly, disrupting mitotic spindle formation. The combination leverages complementary mechanisms to enhance cytotoxic effects against cancer cells.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

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Frequently asked questions about Epirubicin with a Taxane

What is Epirubicin with a Taxane?

Epirubicin with a Taxane is a Chemotherapy combination (anthracycline + microtubule stabilizer) drug developed by Pfizer, indicated for Breast cancer (early-stage and metastatic), Gastric cancer, Ovarian cancer.

How does Epirubicin with a Taxane work?

Epirubicin and taxanes work together as chemotherapy agents that damage cancer cell DNA and disrupt microtubule formation, respectively, to kill rapidly dividing tumor cells.

What is Epirubicin with a Taxane used for?

Epirubicin with a Taxane is indicated for Breast cancer (early-stage and metastatic), Gastric cancer, Ovarian cancer.

Who makes Epirubicin with a Taxane?

Epirubicin with a Taxane is developed by Pfizer (see full Pfizer pipeline at /company/pfizer).

Is Epirubicin with a Taxane also known as anything else?

Epirubicin with a Taxane is also known as Epirubicin, ellence,.

What drug class is Epirubicin with a Taxane in?

Epirubicin with a Taxane belongs to the Chemotherapy combination (anthracycline + microtubule stabilizer) class. See all Chemotherapy combination (anthracycline + microtubule stabilizer) drugs at /class/chemotherapy-combination-anthracycline-microtubule-stabilizer.

What development phase is Epirubicin with a Taxane in?

Epirubicin with a Taxane is in Phase 3.

What are the side effects of Epirubicin with a Taxane?

Common side effects of Epirubicin with a Taxane include Neutropenia, Anemia, Thrombocytopenia, Nausea and vomiting, Alopecia, Peripheral neuropathy.

What does Epirubicin with a Taxane target?

Epirubicin with a Taxane targets DNA (epirubicin); β-tubulin/microtubules (taxane) and is a Chemotherapy combination (anthracycline + microtubule stabilizer).

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