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epidural injection
Epidural injection delivers medication directly into the epidural space surrounding the spinal cord to reduce inflammation and pain.
Epidural injection delivers medication directly into the epidural space surrounding the spinal cord to reduce inflammation and pain. Used for Radiculopathy and nerve root pain, Spinal stenosis-related pain, Herniated disc with radicular symptoms.
At a glance
| Generic name | epidural injection |
|---|---|
| Also known as | Pain- catheter, local anesthetic |
| Sponsor | Taipei Medical University WanFang Hospital |
| Drug class | Corticosteroid injection (epidural administration) |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Neurology |
| Phase | FDA-approved |
Mechanism of action
Epidural injections typically contain corticosteroids and/or local anesthetics that are administered into the epidural space to reduce inflammation of nerve roots and surrounding tissues. The medication diffuses across the dura mater to reach inflamed nerves, providing pain relief and reducing swelling. This approach allows for targeted delivery with lower systemic exposure compared to oral medications.
Approved indications
- Radiculopathy and nerve root pain
- Spinal stenosis-related pain
- Herniated disc with radicular symptoms
- Post-operative pain management
Common side effects
- Headache
- Transient increase in pain
- Infection at injection site
- Dural puncture
- Temporary leg weakness
Key clinical trials
- Examining Analgesic Synergy and Efficacy in Trauma Care (PHASE4)
- CE-STAND: Cervical Epidural STimulation After Neurologic Damage (PHASE1, PHASE2)
- Procedural Framing and Epidural Steroid Injection Outcomes (NA)
- Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
- Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain
- Dose Dependent Steroid Injections (PHASE4)
- Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy (PHASE4)
- Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- epidural injection CI brief — competitive landscape report
- epidural injection updates RSS · CI watch RSS
- Taipei Medical University WanFang Hospital portfolio CI