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Enoxaparin Injectable Solution

Medical University of Vienna · FDA-approved active Small molecule

Enoxaparin is a low-molecular-weight heparin that inhibits blood clotting by enhancing the activity of antithrombin III against factors Xa and IIa.

Enoxaparin is a low-molecular-weight heparin that inhibits blood clotting by enhancing the activity of antithrombin III against factors Xa and IIa. Used for Prevention of venous thromboembolism in surgical patients, Treatment of deep vein thrombosis and pulmonary embolism, Acute coronary syndrome (unstable angina and non-ST-elevation myocardial infarction).

At a glance

Generic nameEnoxaparin Injectable Solution
SponsorMedical University of Vienna
Drug classLow-molecular-weight heparin (LMWH)
TargetAntithrombin III (indirect); Coagulation factors Xa and IIa
ModalitySmall molecule
Therapeutic areaCardiovascular
PhaseFDA-approved

Mechanism of action

Enoxaparin binds to and potentiates antithrombin III, a natural anticoagulant, leading to inactivation of coagulation factors Xa and IIa. This prevents thrombin generation and fibrin clot formation. It is used to prevent and treat venous thromboembolism and acute coronary syndromes.

Approved indications

Common side effects

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