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Endoscopic injection of Indocyanine green
Endoscopic injection of Indocyanine green is a Fluorescent imaging agent Small molecule drug developed by Ukrainian Society of Clinical Oncology. It is currently in Phase 3 development for Intraoperative visualization during endoscopic oncologic surgery, Sentinel lymph node identification in cancer surgery.
Indocyanine green is a near-infrared fluorescent dye injected endoscopically to enable real-time visualization of tissue perfusion and lymphatic drainage during surgical procedures.
Indocyanine green is a near-infrared fluorescent dye injected endoscopically to enable real-time visualization of tissue perfusion and lymphatic drainage during surgical procedures. Used for Intraoperative visualization during endoscopic oncologic surgery, Sentinel lymph node identification in cancer surgery.
At a glance
| Generic name | Endoscopic injection of Indocyanine green |
|---|---|
| Sponsor | Ukrainian Society of Clinical Oncology |
| Drug class | Fluorescent imaging agent |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
Indocyanine green (ICG) is a tricarbocyanine dye that fluoresces in the near-infrared spectrum when excited by appropriate wavelengths. When injected endoscopically, it binds to plasma proteins and accumulates in tissues, allowing surgeons to visualize vascular perfusion, identify sentinel lymph nodes, and delineate tumor margins in real-time using specialized imaging equipment. This enhanced visualization aids in surgical guidance and completeness of resection in oncologic procedures.
Approved indications
- Intraoperative visualization during endoscopic oncologic surgery
- Sentinel lymph node identification in cancer surgery
Common side effects
- Allergic reaction
- Anaphylaxis
- Transient hypotension
Key clinical trials
- Fluorescence Guided Laparoscopic-Endoscopic Cooperative Sentinel Lymph Node Navigation Surgery Strategy for Early Gastric Cancer (NA)
- Confirming the Accuracy of Endoscopic Marking Using a New Marker, a Novel Luminomarker, in Lesion Marking Before Colorectal Cancer Surgery. (NA)
- Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery (PHASE1, PHASE2)
- Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma (NA)
- Fluorescent Approach for Refined Endoscopic Marking With Clip Localization and Identification Procedure (PHASE2)
- Fluorescent Cholangiography vs White Light for Bile Ducts Identification (NA)
- Magnetic Sentinel Lymph Node Mapping in Upper Gastro-Intestinal Cancer: A Feasibility Clinical Investigation (NA)
- Fluorescence Lymph Node Mapping for Colon Cancer Surgery (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Endoscopic injection of Indocyanine green CI brief — competitive landscape report
- Endoscopic injection of Indocyanine green updates RSS · CI watch RSS
- Ukrainian Society of Clinical Oncology portfolio CI
Frequently asked questions about Endoscopic injection of Indocyanine green
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Related
- Drug class: All Fluorescent imaging agent drugs
- Manufacturer: Ukrainian Society of Clinical Oncology — full pipeline
- Therapeutic area: All drugs in Oncology
- Indication: Drugs for Intraoperative visualization during endoscopic oncologic surgery
- Indication: Drugs for Sentinel lymph node identification in cancer surgery
- Compare: Endoscopic injection of Indocyanine green vs similar drugs
- Pricing: Endoscopic injection of Indocyanine green cost, discount & access