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Elunate®

Hutchmed · Phase 2 active Small molecule

Elunate is a small molecule inhibitor of the serine protease inhibitor, serpin family F member 5 (SERPINFB).

Elunate is a small molecule inhibitor of the serine protease inhibitor, serpin family F member 5 (SERPINFB). Used for Advanced or metastatic non-small cell lung cancer, Advanced or metastatic gastric cancer.

At a glance

Generic nameElunate®
Also known asFruquintinib
SponsorHutchmed
Drug classserine protease inhibitor
TargetSERPINFB
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 2

Mechanism of action

Elunate works by inhibiting the activity of SERPINFB, which is involved in the regulation of angiogenesis and tumor growth. This inhibition leads to the reduction of tumor growth and metastasis.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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