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β-elemene
β-elemene is a sesquiterpene compound that has been shown to have anti-cancer properties through the inhibition of cell proliferation and induction of apoptosis.
β-elemene is a sesquiterpene compound that has been shown to have anti-cancer properties through the inhibition of cell proliferation and induction of apoptosis. Used for Non-small cell lung cancer, Breast cancer.
At a glance
| Generic name | β-elemene |
|---|---|
| Also known as | elemene liposomes |
| Sponsor | Sun Yat-sen University |
| Drug class | sesquiterpene |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
β-elemene has been found to exert its anti-cancer effects through multiple mechanisms, including the inhibition of the PI3K/AKT signaling pathway and the induction of cell cycle arrest. Additionally, β-elemene has been shown to have anti-inflammatory and anti-oxidative properties, which may contribute to its anti-cancer effects.
Approved indications
- Non-small cell lung cancer
- Breast cancer
Common side effects
- Nausea
- Vomiting
- Fatigue
Key clinical trials
- A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant Gliomas (PHASE3)
- β-elemene Combine With EGFR-TKI for Advanced EGFR-TKI-resistant NSCLC (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |