Last reviewed 2026-04-23 · How we verify

Electrical-first

Electrical-first drug modulates electrical activity in the heart.

Electrical-first drug modulates electrical activity in the heart. Used for Supraventricular tachycardia, Atrial fibrillation for stroke prevention.

At a glance

Mechanism of action

This is achieved through the regulation of ion channels and electrical impulses, which can help to prevent arrhythmias and improve cardiac function.

Approved indications

• Supraventricular tachycardia
• Atrial fibrillation for stroke prevention

Common side effects

• Bradycardia
• Nausea
• Dizziness

Key clinical trials

• TEAS for Ipsilateral Shoulder Pain After Video-Assisted Thoracoscopic Lung Surgery (NA)
• Deep Brain Stimulation for Severe Self-Injurious Behaviour in Children (NA)
• Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3 (PHASE3)
• Innovative Closed-loop Functional Electrical Stimulation Control System for Augmenting Post-stroke Gait (NA)
• Targeted Transcranial Magnetic Stimulation to Improve Hippocampal-dependent Declarative Memory Abilities (NA)
• Biomechanical and Functional Effects of Adding Sensory-Threshold Electrical Stimulation to Neurodevelopmental Therapy in Children With Spastic Cerebral Palsy: A Single-Arm Repeated-Measures Study (NA)
• Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the Neck (NA)
• Optimization and Validation of Electric Acoustic Stimulation (EAS) Mapping as a Function of Residual Hearing After CI-Implantation (NA)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.