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EC to docetaxel or paclitaxel
EC to docetaxel or paclitaxel is a Chemotherapy combination regimen Small molecule drug developed by RenJi Hospital. It is currently in Phase 3 development for Breast cancer (likely early-stage or locally advanced, based on typical EC→taxane use). Also known as: Taxol.
EC (epirubicin/cyclophosphamide) followed by docetaxel or paclitaxel is a sequential chemotherapy regimen that damages cancer cell DNA and disrupts microtubule function to inhibit tumor growth.
EC (epirubicin/cyclophosphamide) followed by docetaxel or paclitaxel is a sequential chemotherapy regimen that damages cancer cell DNA and disrupts microtubule function to inhibit tumor growth. Used for Breast cancer (likely early-stage or locally advanced, based on typical EC→taxane use).
At a glance
| Generic name | EC to docetaxel or paclitaxel |
|---|---|
| Also known as | Taxol |
| Sponsor | RenJi Hospital |
| Drug class | Chemotherapy combination regimen |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
This is a multi-agent chemotherapy combination where epirubicin and cyclophosphamide (EC) are administered first as DNA-damaging agents, followed by taxane chemotherapy (docetaxel or paclitaxel) which stabilizes microtubules and prevents cell division. The sequential approach is designed to maximize efficacy while managing cumulative toxicity, commonly used in breast cancer treatment.
Approved indications
- Breast cancer (likely early-stage or locally advanced, based on typical EC→taxane use)
Common side effects
- Neutropenia
- Anemia
- Thrombocytopenia
- Nausea/vomiting
- Alopecia
- Peripheral neuropathy
- Fatigue
- Mucositis
- Cardiotoxicity
Key clinical trials
- Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer (PHASE2)
- Pyrotinib Plus Neoadjuvant Chemotherapy in HR+/HER2-, HER4-High Breast Cancer (PHASE2)
- Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer (PHASE2)
- Study Comparing EC-T Verses PCb in the Adjuvant Chemotherapy of Non-triple Negative Breast Cancer (PHASE3)
- Addition of Cisplatin to Adjuvant Chemotherapy for Early Stage Breast Cancer in High-Risk Women (PHASE3)
- Adjuvant Palbociclib in Elderly Patients With Breast Cancer (PHASE2)
- A Study of Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Operable HER2-Positive Primary Breast Cancer (PHASE3)
- A Randomized Controlled Trial of HER-2 Positive Breast Cancer Patients Treated With Lapatinib vs Herceptin (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- EC to docetaxel or paclitaxel CI brief — competitive landscape report
- EC to docetaxel or paclitaxel updates RSS · CI watch RSS
- RenJi Hospital portfolio CI
Frequently asked questions about EC to docetaxel or paclitaxel
What is EC to docetaxel or paclitaxel?
How does EC to docetaxel or paclitaxel work?
What is EC to docetaxel or paclitaxel used for?
Who makes EC to docetaxel or paclitaxel?
Is EC to docetaxel or paclitaxel also known as anything else?
What drug class is EC to docetaxel or paclitaxel in?
What development phase is EC to docetaxel or paclitaxel in?
What are the side effects of EC to docetaxel or paclitaxel?
Related
- Drug class: All Chemotherapy combination regimen drugs
- Manufacturer: RenJi Hospital — full pipeline
- Therapeutic area: All drugs in Oncology
- Indication: Drugs for Breast cancer (likely early-stage or locally advanced, based on typical EC→taxane use)
- Also known as: Taxol
- Compare: EC to docetaxel or paclitaxel vs similar drugs
- Pricing: EC to docetaxel or paclitaxel cost, discount & access