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doxepin solution
Doxepin solution is a tricyclic antidepressant that works by inhibiting the reuptake of serotonin and norepinephrine.
Doxepin solution is a tricyclic antidepressant that works by inhibiting the reuptake of serotonin and norepinephrine. Used for Depression, Anxiety.
At a glance
| Generic name | doxepin solution |
|---|---|
| Sponsor | Nanfang Hospital, Southern Medical University |
| Drug class | tricyclic antidepressant |
| Modality | Small molecule |
| Therapeutic area | Psychiatry |
| Phase | Phase 3 |
Mechanism of action
This action increases the levels of these neurotransmitters in the brain, which helps to improve mood and reduce symptoms of depression. Doxepin also has antihistamine and anticholinergic effects, which can contribute to its therapeutic and side effect profiles.
Approved indications
- Depression
- Anxiety
Common side effects
- Drowsiness
- Dry mouth
- Dizziness
- Constipation
- Weight gain
Key clinical trials
- Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy (PHASE3)
- Doxepin Solution for Alleviation of Stubborn Breakthrough Pain Induced by Swallowing in Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma (NA)
- Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% As a New Surrogate Model of Itch (NA)
- Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- doxepin solution CI brief — competitive landscape report
- doxepin solution updates RSS · CI watch RSS
- Nanfang Hospital, Southern Medical University portfolio CI