Last reviewed · How we verify

Dose reduction

University Hospital, Ghent · FDA-approved active Small molecule

Dose reduction is a clinical strategy that lowers the administered amount of an active pharmaceutical ingredient to minimize toxicity while maintaining therapeutic benefit.

At a glance

Generic nameDose reduction
SponsorUniversity Hospital, Ghent
ModalitySmall molecule
PhaseFDA-approved

Mechanism of action

Dose reduction is not a drug itself, but rather a dosing adjustment strategy employed in clinical practice, particularly in oncology and other therapeutic areas where dose-limiting toxicities occur. It involves decreasing the standard dose of an established medication to improve tolerability and safety profiles while preserving efficacy. This approach is commonly used when patients experience severe adverse events or have compromised organ function.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results