Last reviewed · How we verify
Dobutamine Hydrochloride In Dextrose 5% In Plastic Container (DOBUTAMINE)
At a glance
| Generic name | DOBUTAMINE |
|---|---|
| Sponsor | Lilly |
| Drug class | beta-Adrenergic Agonist |
| Target | Beta-2 adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
| First approval | 1978 |
Approved indications
- Cardiac Decompensation
- Cardiac Decompensation Post Cardiac Surgery
- Cardiogenic shock
- Decompensated cardiac failure
- Organic Cardiac Disease
- Stress echocardiography using dobutamine
Common side effects
- Appendicolith
- Multiple organ dysfunction syndrome
- Appendicitis
- Ventricular fibrillation
- Ascites
- Stress
- Blood phosphorus increased
- Abdominal distension
- Sepsis
- Hyponatraemia
- Cardiogenic shock
- General physical health deterioration
Drug interactions
- linezolid
Key clinical trials
- Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock (NA)
- Artificial Intelligence Stress Echo (FINESSE) Project
- Impact Of Using LevosemidanVersus DobutamineOn Right Ventricular Function In AdultPatients Undergoing Elective Valve Replacement Surgery
- The PROTECT-HIE Trial (PHASE2)
- Cerebral Oxygen Saturation Monitoring In Cardiac Surgery (COSMICS) (NA)
- Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study (NA)
- Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension
- Comparison Bewteen Intraoperative HPI vs. High Mean Arterial Pressure Threshold (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |