What is DIT112 used for?

DIT112 is indicated for Type 2 diabetes, Heart failure.

What are the side effects of DIT112?

Common side effects include Nausea, Diarrhea, Vomiting, Hypotension, Increased urination.

Last reviewed 2026-04-23 · How we verify

DIT112

EMS · Phase 3 active Small molecule

DIT112 is a small molecule that targets the SGLT2 receptor.

DIT112 is a small molecule that targets the SGLT2 receptor. Used for Type 2 diabetes, Heart failure.

At a glance

Generic name	DIT112
Sponsor	EMS
Drug class	SGLT2 inhibitor
Target	SGLT2
Modality	Small molecule
Therapeutic area	Diabetes
Phase	Phase 3

Mechanism of action

By inhibiting SGLT2, DIT112 reduces glucose reabsorption in the kidneys, thereby lowering blood glucose levels. This mechanism is particularly beneficial for patients with type 2 diabetes. DIT112's SGLT2 inhibition also has a secondary effect of reducing sodium reabsorption, which may contribute to its cardiovascular benefits.

Approved indications

Type 2 diabetes
Heart failure

Common side effects

Nausea
Diarrhea
Vomiting
Hypotension
Increased urination

Key clinical trials

Efficacy and Safety of DIT112 in the Treatment of Moderate to Severe Pain After Dental Surgery for the Extraction of Impacted Third Molars (PHASE3)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results