Last reviewed 2026-05-24 · How we verify

Dicuman (dicoumarol)

AbbVie · FDA-approved active Under review Quality 10/100

Dicuman (generic name: dicoumarol) is a dicoumarol drug developed by AbbVie. It is currently FDA-approved (first approved 1944) for Cerebral embolism, Myocardial infarction, Prevention of Cerebral Thrombosis.

Dicoumarol is a small molecule inhibitor that targets Vitamin K epoxide reductase complex subunit 1, specifically inhibiting isoform 1. It is a naturally occurring anticoagulant drug that depletes stores of vitamin K.

At a glance

Generic name	dicoumarol
Sponsor	AbbVie
Drug class	dicoumarol
Target	NAD(P)H dehydrogenase [quinone] 1
Therapeutic area	Cardiovascular
Phase	FDA-approved
First approval	1944

Approved indications

Cerebral embolism
Myocardial infarction
Prevention of Cerebral Thrombosis
Thromboembolic disorder
Thrombosis

Common side effects

No common side effects on file.

Drug interactions

Vitamin E
colesevelam
diflunisal
disulfiram
erythromycin
etodolac
fenoprofen
fluconazole
flurbiprofen
fluvastatin
fosphenytoin
ibuprofen

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
FDA label	Mechanism, indications, dosing, boxed warnings, drug interactions

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Dicuman CI brief — competitive landscape report
Dicuman updates RSS · CI watch RSS
AbbVie portfolio CI

Frequently asked questions about Dicuman

What is Dicuman?

Dicuman (dicoumarol) is a dicoumarol drug developed by AbbVie, indicated for Cerebral embolism, Myocardial infarction, Prevention of Cerebral Thrombosis.

What is Dicuman used for?

Dicuman is indicated for Cerebral embolism, Myocardial infarction, Prevention of Cerebral Thrombosis, Thromboembolic disorder, Thrombosis.

Who makes Dicuman?

Dicuman is developed and marketed by AbbVie (see full AbbVie pipeline at /company/abbvie).

What is the generic name of Dicuman?

dicoumarol is the generic (nonproprietary) name of Dicuman.

What drug class is Dicuman in?

Dicuman belongs to the dicoumarol class. See all dicoumarol drugs at /class/dicoumarol.

When was Dicuman approved?

Dicuman was first approved on 1944.

What development phase is Dicuman in?

Dicuman is FDA-approved (marketed).

What does Dicuman target?

Dicuman targets NAD(P)H dehydrogenase [quinone] 1 and is a dicoumarol.

Drug class: All dicoumarol drugs
Target: All drugs targeting NAD(P)H dehydrogenase [quinone] 1
Manufacturer: AbbVie — full pipeline
Therapeutic area: All drugs in Cardiovascular
Indication: Drugs for Cerebral embolism
Indication: Drugs for Myocardial infarction
Indication: Drugs for Prevention of Cerebral Thrombosis

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing