Last reviewed 2026-04-22 · How we verify

DHA Omega-3

DHA (docosahexaenoic acid) omega-3 fatty acid reduces inflammation and supports cardiovascular and neurological health through modulation of lipid metabolism and inflammatory pathways.

DHA (docosahexaenoic acid) omega-3 fatty acid reduces inflammation and supports cardiovascular and neurological health through modulation of lipid metabolism and inflammatory pathways. Used for Hypertriglyceridemia, Cardiovascular disease prevention, Cognitive health / Neurological support.

At a glance

Mechanism of action

DHA is a long-chain polyunsaturated omega-3 fatty acid that incorporates into cell membranes and reduces production of pro-inflammatory eicosanoids and cytokines. It also activates specialized pro-resolving mediators that actively resolve inflammation. DHA has been shown to improve lipid profiles, reduce triglycerides, and support endothelial function and cognitive health.

Approved indications

• Hypertriglyceridemia
• Cardiovascular disease prevention
• Cognitive health / Neurological support

Common side effects

• Gastrointestinal upset
• Fishy aftertaste
• Bleeding risk (at high doses)

Key clinical trials

• Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia (PHASE2)
• Heart & Health Study (NA)
• Effect of a Parenteral Emulsion With Omega3 on Neonates With PPHN and CDH (PHASE2)
• OMEGA - Dietary Intervention - COPD Trial (NA)
• Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids (NA)
• Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms (EARLY_PHASE1)
• Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery (NA)
• Observing Metabolism of EPA With Consideration of Genetics And Sex (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.