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Dextrose Water
Dextrose water provides a source of glucose and free water for intravenous administration to maintain hydration and supply carbohydrate calories.
Dextrose water provides a source of glucose and free water for intravenous administration to maintain hydration and supply carbohydrate calories. Used for Fluid and electrolyte replacement, Provision of carbohydrate calories in patients unable to take oral nutrition, Maintenance of hydration in hospitalized patients.
At a glance
| Generic name | Dextrose Water |
|---|---|
| Also known as | PRP |
| Sponsor | University of Michigan |
| Drug class | Intravenous fluid / Carbohydrate solution |
| Modality | Small molecule |
| Therapeutic area | Supportive Care / Fluid and Electrolyte Management |
| Phase | FDA-approved |
Mechanism of action
Dextrose water is a simple intravenous fluid containing glucose dissolved in sterile water. When administered, it provides both hydration (via the water component) and a readily metabolizable carbohydrate source (via dextrose/glucose) that can be used for energy production. It is commonly used in clinical settings to maintain fluid balance, prevent dehydration, and provide modest caloric support, particularly in patients unable to take oral nutrition.
Approved indications
- Fluid and electrolyte replacement
- Provision of carbohydrate calories in patients unable to take oral nutrition
- Maintenance of hydration in hospitalized patients
Common side effects
- Hyperglycemia
- Phlebitis at infusion site
- Fluid overload
- Hypokalemia
Key clinical trials
- Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion (NA)
- Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise (NA)
- A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors (PHASE1, PHASE2)
- To Determine the Effect of Phaseolean on Glycemic Response to Carbohydrate Rich Meal in Healthy Adult Human Participants (NA)
- Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes (NA)
- Glycaemic Index Measurement of an Oral Nutritional Supplement With Biomarker Assessment and Lifestyle Monitoring in Healthy Participants (NA)
- The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery (PHASE4)
- Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |