What is Dextrofenfluramine used for?

Dextrofenfluramine is indicated for Obesity.

What development phase is Dextrofenfluramine in?

Dextrofenfluramine is FDA-approved (marketed).

What is the generic name of Dextrofenfluramine?

DEXFENFLURAMINE is the generic (nonproprietary) name of Dextrofenfluramine.

Last reviewed 2026-04-20 · How we verify

Dextrofenfluramine (DEXFENFLURAMINE)

FDA-approved withdrawn Small molecule Quality 31/100

At a glance

Generic name	DEXFENFLURAMINE
Drug class	dexfenfluramine
Target	Alpha-1B adrenergic receptor
Modality	Small molecule
Therapeutic area	Metabolic
Phase	FDA-approved

Approved indications

Obesity

Common side effects

No common side effects on file.

Drug interactions

isocarboxazid
phenelzine
selegiline
tranylcypromine

Key clinical trials

Multiple Doses of DM199 in Patients With Chronic Kidney Disease (REDUX) (PHASE2)
Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging (NA)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Dextrofenfluramine CI brief — competitive landscape report
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