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Desogestrel medium follicular phase

Centre Hospitalier Intercommunal Creteil · Phase 3 active Small molecule

Desogestrel is a progestin that prevents pregnancy by suppressing ovulation and altering cervical mucus and endometrial conditions.

Desogestrel is a progestin that prevents pregnancy by suppressing ovulation and altering cervical mucus and endometrial conditions. Used for Contraception / prevention of pregnancy.

At a glance

Generic nameDesogestrel medium follicular phase
SponsorCentre Hospitalier Intercommunal Creteil
Drug classProgestin (hormonal contraceptive)
TargetProgesterone receptor
ModalitySmall molecule
Therapeutic areaContraception / Reproductive Health
PhasePhase 3

Mechanism of action

Desogestrel is a third-generation synthetic progestin used in hormonal contraceptives. It works primarily by inhibiting the luteinizing hormone (LH) surge needed to trigger ovulation. Additionally, it increases cervical mucus viscosity to impede sperm penetration and alters the endometrium to reduce implantation likelihood. The 'medium follicular phase' designation refers to the timing or dosing regimen within a multiphasic oral contraceptive formulation.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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