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Depigoid Parietaria judaica 1000DPP/ml
Depigoid Parietaria judaica 1000DPP/ml is a Allergen immunotherapy extract Biologic drug developed by Laboratorios Leti, S.L.. It is currently in Phase 3 development for Allergic rhinitis caused by Parietaria judaica pollen sensitization, Allergic asthma associated with Parietaria judaica pollen allergy. Also known as: A suspension of depigmented and glutaraldehyde-polymerised allergen extract of Parietaria judaica adsorbed onto aluminium hydroxide..
Depigoid is an allergen extract-based immunotherapeutic that desensitizes the immune system to Parietaria judaica pollen through gradual exposure, reducing allergic responses.
Depigoid is an allergen extract-based immunotherapeutic that desensitizes the immune system to Parietaria judaica pollen through gradual exposure, reducing allergic responses. Used for Allergic rhinitis caused by Parietaria judaica pollen sensitization, Allergic asthma associated with Parietaria judaica pollen allergy.
At a glance
| Generic name | Depigoid Parietaria judaica 1000DPP/ml |
|---|---|
| Also known as | A suspension of depigmented and glutaraldehyde-polymerised allergen extract of Parietaria judaica adsorbed onto aluminium hydroxide. |
| Sponsor | Laboratorios Leti, S.L. |
| Drug class | Allergen immunotherapy extract |
| Modality | Biologic |
| Therapeutic area | Immunology / Allergy |
| Phase | Phase 3 |
Mechanism of action
Depigoid contains standardized allergen extracts from Parietaria judaica (wall pellitory) pollen and works through allergen immunotherapy (AIT) principles. By administering increasing doses of the allergen, it promotes immune tolerance through shift toward regulatory T cells and IgG-blocking antibodies, thereby reducing IgE-mediated allergic reactions. This approach is designed to provide long-term clinical benefit and reduce symptoms in allergic rhinitis and potentially allergic asthma.
Approved indications
- Allergic rhinitis caused by Parietaria judaica pollen sensitization
- Allergic asthma associated with Parietaria judaica pollen allergy
Common side effects
- Local injection site reactions (itching, swelling, erythema)
- Oral allergy syndrome or local oral symptoms
- Systemic allergic reactions
- Rhinitis or asthma exacerbation
Key clinical trials
- Subcutaneous Immunotherapy Treatment for Patients With Hypersensitivity to Parietaria Judaica (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Depigoid Parietaria judaica 1000DPP/ml CI brief — competitive landscape report
- Depigoid Parietaria judaica 1000DPP/ml updates RSS · CI watch RSS
- Laboratorios Leti, S.L. portfolio CI
Frequently asked questions about Depigoid Parietaria judaica 1000DPP/ml
What is Depigoid Parietaria judaica 1000DPP/ml?
How does Depigoid Parietaria judaica 1000DPP/ml work?
What is Depigoid Parietaria judaica 1000DPP/ml used for?
Who makes Depigoid Parietaria judaica 1000DPP/ml?
Is Depigoid Parietaria judaica 1000DPP/ml also known as anything else?
What drug class is Depigoid Parietaria judaica 1000DPP/ml in?
What development phase is Depigoid Parietaria judaica 1000DPP/ml in?
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Related
- Drug class: All Allergen immunotherapy extract drugs
- Manufacturer: Laboratorios Leti, S.L. — full pipeline
- Therapeutic area: All drugs in Immunology / Allergy
- Indication: Drugs for Allergic rhinitis caused by Parietaria judaica pollen sensitization
- Indication: Drugs for Allergic asthma associated with Parietaria judaica pollen allergy
- Also known as: A suspension of depigmented and glutaraldehyde-polymerised allergen extract of Parietaria judaica adsorbed onto aluminium hydroxide.