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Dentifrice Paste
A dentifrice paste that mechanically removes plaque and debris while delivering active ingredients to clean and protect teeth and gums.
A dentifrice paste that mechanically removes plaque and debris while delivering active ingredients to clean and protect teeth and gums. Used for Plaque removal and dental caries prevention, Oral hygiene maintenance.
At a glance
| Generic name | Dentifrice Paste |
|---|---|
| Sponsor | Dr. D. Y. Patil Dental College & Hospital |
| Modality | Small molecule |
| Therapeutic area | Dental/Oral Health |
| Phase | FDA-approved |
Mechanism of action
Dentifrice pastes are oral hygiene products designed to be used with a toothbrush to remove food particles, plaque biofilm, and surface stains from teeth. They typically contain abrasive agents for mechanical cleaning, detergents for foaming and emulsification, and may include fluoride or other therapeutic agents to strengthen enamel and prevent dental caries. The formulation supports mechanical plaque removal and may provide antimicrobial or desensitizing benefits depending on active ingredients.
Approved indications
- Plaque removal and dental caries prevention
- Oral hygiene maintenance
Common side effects
- Tooth sensitivity
- Gum irritation
- Allergic reaction to ingredients
Key clinical trials
- Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis. (PHASE2)
- Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal (NA)
- Comparative Effectiveness of Remineralization Agents on Attachment-Associated Demineralization in Clear Aligner Patients (NA)
- A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control (NA)
- Comparative Analysis of Interventions for Prevention of Dental Caries in School Children (NA)
- Hydroxyapatite vs Fluoride Toothpaste for MIH Remineralization (PHASE2)
- Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children (NA)
- A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Dentifrice Paste CI brief — competitive landscape report
- Dentifrice Paste updates RSS · CI watch RSS
- Dr. D. Y. Patil Dental College & Hospital portfolio CI