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DAPT, Statin
DAPT inhibits platelet aggregation by blocking the P2Y12 receptor.
DAPT inhibits platelet aggregation by blocking the P2Y12 receptor. Used for Acute coronary syndrome, Myocardial infarction, Ischemic stroke.
At a glance
| Generic name | DAPT, Statin |
|---|---|
| Also known as | DES, BMS |
| Sponsor | Samsung Medical Center |
| Drug class | Antiplatelet |
| Target | P2Y12 receptor |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 2 |
Mechanism of action
DAPT works by selectively and reversibly inhibiting the P2Y12 receptor on platelet surfaces, which prevents adenosine diphosphate (ADP) from binding and activating platelets. This action reduces platelet aggregation and subsequent thrombus formation.
Approved indications
- Acute coronary syndrome
- Myocardial infarction
- Ischemic stroke
Common side effects
- Bleeding
- Thrombocytopenia
- Cerebrovascular accident
Key clinical trials
- A Polypill for Acute Coronary Syndrome (PHASE2)
- Anti-inflammatory Therapy for Recurrent In-stent Restenosis (PHASE4)
- Effect of L-Carnitine on Biomarkers of Myocardial Reperfusion Injury in Patients With STEMI (PHASE2)
- Efficacy and Safety Study of Endovascular Treatment of Asymptomatic Carotid Artery Stenosis (NA)
- Alpha Lipoic Acid Effect on No-Reflow Phenomenon (NA)
- Prognostic Value of Precision Medicine in Patients With MINOCA (PROMISE Trial). (PHASE4)
- Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis (PHASE3)
- The Effect of Early Administration of Dapagliflozin in STEMI Patients With LV Systolic Dysfunction (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DAPT, Statin CI brief — competitive landscape report
- DAPT, Statin updates RSS · CI watch RSS
- Samsung Medical Center portfolio CI