Last reviewed · How we verify

Dalbavancin via Intraperitoneal Administration

University of Colorado, Denver · FDA-approved active Small molecule

Dalbavancin is a lipoglycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to D-Ala-D-Ala peptidoglycan precursors.

Dalbavancin is a lipoglycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to D-Ala-D-Ala peptidoglycan precursors. Used for Intra-abdominal infections via intraperitoneal administration, Peritonitis in peritoneal dialysis patients.

At a glance

Generic nameDalbavancin via Intraperitoneal Administration
SponsorUniversity of Colorado, Denver
Drug classLipoglycopeptide antibiotic
TargetBacterial peptidoglycan (D-Ala-D-Ala)
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhaseFDA-approved

Mechanism of action

Dalbavancin works by disrupting the cross-linking of peptidoglycan in bacterial cell walls, similar to vancomycin but with enhanced potency and a longer half-life. When administered intraperitoneally, it achieves high local concentrations in the peritoneal cavity to treat intra-abdominal infections. The intraperitoneal route allows direct delivery to the infection site while minimizing systemic exposure.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: