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curcumin paste
Curcumin is a polyphenolic compound that exerts anti-inflammatory and antioxidant effects by inhibiting multiple signaling pathways including NF-κB and reducing reactive oxygen species.
Curcumin is a polyphenolic compound that exerts anti-inflammatory and antioxidant effects by inhibiting multiple signaling pathways including NF-κB and reducing reactive oxygen species. Used for Inflammatory conditions (general), Antioxidant support.
At a glance
| Generic name | curcumin paste |
|---|---|
| Sponsor | Ain Shams University |
| Drug class | Natural product/polyphenol |
| Target | NF-κB, multiple targets (non-selective) |
| Modality | Small molecule |
| Therapeutic area | Anti-inflammatory/Antioxidant |
| Phase | FDA-approved |
Mechanism of action
Curcumin, the active constituent of turmeric, modulates inflammatory mediators and transcription factors involved in chronic disease pathogenesis. It acts as a free radical scavenger and suppresses pro-inflammatory cytokine production, making it relevant for conditions characterized by chronic inflammation and oxidative stress.
Approved indications
- Inflammatory conditions (general)
- Antioxidant support
Common side effects
- Gastrointestinal upset
- Mild nausea
- Staining of oral mucosa
Key clinical trials
- The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen Planus (NA)
- Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing (PHASE2)
- Effect of Hebal and Synthetic Medicamentss on Enterococcus Feacalis (PHASE2, PHASE3)
- aPDT for the Remediation of Dental Black Stain (NA)
- Curcumin-Simvastatin-EDTA in the Treatment of Periodontitis (PHASE4)
- Curcumin Paste as an Adjunctive Therapy in Periodontitis (PHASE4)
- The Effect of Topical Curcumin Versus Topical Corticosteroid on Management of Oral Lichen Planus Patients (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- curcumin paste CI brief — competitive landscape report
- curcumin paste updates RSS · CI watch RSS
- Ain Shams University portfolio CI