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Methylguanidoacetic Acid (CREATINE)
Methylguanidoacetic Acid, also known as Creatine, is a small molecule drug in the creatine class. It is used to increase muscle strength and endurance, particularly in athletes and individuals with muscle-wasting diseases. The commercial status of Creatine is complex, as it is available both as a patented supplement and as a generic product. Key safety considerations include potential gastrointestinal side effects and interactions with certain medications. As a dietary supplement, Creatine is not regulated by the FDA in the same way as prescription medications.
At a glance
| Generic name | CREATINE |
|---|---|
| Drug class | creatine |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Intranasal Administration of Dodecyl Creatine Ester (CBT101) in Healthy Male Subjects (PHASE1)
- Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies (PHASE1)
- Camel Milk Impact on Aerobic Exercise Recovery, Induced Inflammation, and Physical Performance (NA)
- Effect of Creatine Supplementation on Physical Performance in Vegan Subjects (NA)
- Increased Dietary Protein Intake During GLP-1 Medication Use (in Middle-aged Women With Overweight/Obesity) (NA)
- Effects of Short-term Acute Creatine Supplementation on Power, Speed and Muscular Strengths in Young Football Players (NA)
- Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat (NA)
- Creatine Supplementation and Resistance Training to Improve Sarcopenia Parameters in Patients With Prostate Cancer After Androgen Deprivation Therapy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |