Last reviewed · How we verify

CP-690,550 Ointment 1

Pfizer · Phase 2 active Small molecule

CP-690,550 is a Janus kinase (JAK) inhibitor.

CP-690,550 is a Janus kinase (JAK) inhibitor. Used for Rheumatoid arthritis.

At a glance

Generic nameCP-690,550 Ointment 1
SponsorPfizer
Drug classJAK inhibitor
TargetJAK3
ModalitySmall molecule
Therapeutic areaImmunology
PhasePhase 2

Mechanism of action

JAK inhibitors block the activity of Janus kinases, enzymes that play a key role in signaling pathways involved in inflammation and immune responses. By inhibiting these enzymes, CP-690,550 reduces the production of pro-inflammatory cytokines and mediators, thereby exerting anti-inflammatory effects.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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