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COOL-COS
COOL-COS is a medication that works by inhibiting the action of a specific enzyme.
COOL-COS is a medication that works by inhibiting the action of a specific enzyme. Used for Heat stroke prevention and treatment.
At a glance
| Generic name | COOL-COS |
|---|---|
| Also known as | Friendly COS |
| Sponsor | University of Sao Paulo |
| Drug class | small molecule |
| Target | HSP70 |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
COOL-COS is a small molecule inhibitor that targets a key enzyme involved in the regulation of body temperature. By inhibiting this enzyme, COOL-COS helps to reduce body temperature and alleviate symptoms associated with heat-related illnesses.
Approved indications
- Heat stroke prevention and treatment
Common side effects
- Hypothermia
- Nausea
- Headache
Key clinical trials
- COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation (COOL-COS) Associated With Corifollitropin Alfa: a Pilot Study (PHASE1)
- COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |