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Control tetanus vaccine, adsorbed
This vaccine stimulates the immune system to produce antibodies against tetanus toxin by presenting inactivated tetanus toxoid adsorbed onto an aluminum salt adjuvant.
This vaccine stimulates the immune system to produce antibodies against tetanus toxin by presenting inactivated tetanus toxoid adsorbed onto an aluminum salt adjuvant. Used for Prevention of tetanus in infants, children, and adults.
At a glance
| Generic name | Control tetanus vaccine, adsorbed |
|---|---|
| Sponsor | Sinovac Life Sciences Co., Ltd. |
| Drug class | Inactivated bacterial toxoid vaccine |
| Target | Tetanus toxin (tetanospasmin) |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
Tetanus vaccine, adsorbed contains inactivated tetanus toxoid (a detoxified form of the tetanus toxin produced by Clostridium tetani) adsorbed onto aluminum hydroxide or aluminum phosphate. The adjuvant enhances the immunogenicity of the toxoid, promoting a robust humoral immune response that generates protective antibodies against tetanus toxin, conferring immunity against tetanus infection.
Approved indications
- Prevention of tetanus in infants, children, and adults
Common side effects
- Local injection site reactions (pain, erythema, swelling)
- Fever
- Myalgia
- Headache
- Fatigue
Key clinical trials
- A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) (PHASE1)
- Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine (PHASE1, PHASE2)
- A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants (PHASE2)
- Confirmatory Study of BK1310 in Healthy Infants (PHASE3)
- Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine (PHASE1)
- Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand (PHASE3)
- A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (PHASE3)
- Infant Malaria Vaccine Schedule Optimization (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Control tetanus vaccine, adsorbed CI brief — competitive landscape report
- Control tetanus vaccine, adsorbed updates RSS · CI watch RSS
- Sinovac Life Sciences Co., Ltd. portfolio CI