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Control continuous peripheral nerve blocks
A continuous peripheral nerve block system delivers local anesthetic medication directly to peripheral nerves over an extended period to provide prolonged pain relief.
A continuous peripheral nerve block system delivers local anesthetic medication directly to peripheral nerves over an extended period to provide prolonged pain relief. Used for Perioperative pain management following surgery, Chronic pain conditions amenable to peripheral nerve blockade.
At a glance
| Generic name | Control continuous peripheral nerve blocks |
|---|---|
| Also known as | Control perineural local anesthetic infusion |
| Sponsor | University of California, San Diego |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
This is a medical device/technique rather than a traditional pharmaceutical drug. It involves placement of a catheter near a peripheral nerve with continuous or intermittent infusion of local anesthetic (typically liposomal bupivacaine or similar agents) to block nerve conduction and provide anesthesia/analgesia. The system allows for extended pain control beyond single-injection nerve blocks, typically used perioperatively or for chronic pain management.
Approved indications
- Perioperative pain management following surgery
- Chronic pain conditions amenable to peripheral nerve blockade
Common side effects
- Local anesthetic toxicity
- Catheter-related infection
- Nerve injury
- Vascular puncture
Key clinical trials
- From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
- Real-Time Monitoring of the Injection Pressure During the Peripheral Nerve Block (NA)
- Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy (NA)
- Postoperative Pain and Analgesic Use After Total Knee Arthroplasty
- TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant (PHASE4)
- Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery (NA)
- An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service (PHASE3)
- Fascia Iliaca Compartment Block in Total Knee Arthroplasty With Intra-Articular Injection
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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