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Continuous OC (EE/DROS)

University of North Carolina, Chapel Hill · FDA-approved active Small molecule

Continuous OC (EE/DROS) is an oral contraceptive containing ethinyl estradiol and drospirenone that prevents pregnancy through hormonal suppression of ovulation.

Continuous OC (EE/DROS) is an oral contraceptive containing ethinyl estradiol and drospirenone that prevents pregnancy through hormonal suppression of ovulation. Used for Contraception, Reduction of menstrual bleeding.

At a glance

Generic nameContinuous OC (EE/DROS)
Also known asYaz
SponsorUniversity of North Carolina, Chapel Hill
Drug classOral contraceptive
TargetProgesterone receptor, estrogen receptor
ModalitySmall molecule
Therapeutic areaContraception
PhaseFDA-approved

Mechanism of action

This combination oral contraceptive works by delivering a continuous dose of ethinyl estradiol (a synthetic estrogen) and drospirenone (a progestin with antimineralocorticoid activity) to suppress the luteinizing hormone surge required for ovulation. The continuous formulation eliminates the hormone-free interval found in traditional cyclic pills, reducing breakthrough bleeding and providing consistent contraceptive coverage throughout the cycle.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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