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connective tissue graft
A connective tissue graft provides structural support and promotes tissue regeneration by replacing or augmenting damaged or missing connective tissue.
A connective tissue graft provides structural support and promotes tissue regeneration by replacing or augmenting damaged or missing connective tissue. Used for Connective tissue repair and reconstruction, Tendon and ligament repair, Periodontal regeneration.
At a glance
| Generic name | connective tissue graft |
|---|---|
| Also known as | sub epithelial graft, autogenous subepithelial connective tissue graft |
| Sponsor | Abeer hassan sharafuddin |
| Modality | Biologic |
| Therapeutic area | Surgical/Regenerative Medicine |
| Phase | FDA-approved |
Mechanism of action
Connective tissue grafts are biological or synthetic materials used in surgical procedures to restore structural integrity and function to areas where connective tissue (such as tendons, ligaments, or fascia) has been damaged, diseased, or is absent. The graft integrates with host tissue and provides a scaffold for cellular infiltration and tissue remodeling, facilitating healing and restoration of mechanical function.
Approved indications
- Connective tissue repair and reconstruction
- Tendon and ligament repair
- Periodontal regeneration
- Wound coverage and closure
Common side effects
- Graft rejection or failure
- Infection at graft site
- Scarring
- Reduced functional recovery
Key clinical trials
- Treatment Off Gingival Recession Defects Using a Xenogenic Acellular Dermal Matrix Compared to Connective Tissue Graft. (NA)
- Evaluation of the Modified VISTA Technique Using ALB-PRF vs CTG in the Treatment of Multiple Miller Class III Recessions (PHASE2, PHASE3)
- GMEB-SASS: A Gene-Modified Skin Substitute for RDEB Treatment (PHASE1, PHASE2)
- Bi-layer Collagen Membrane Versus Subepithelial Connective Tissue Graft in the Treatment of Localized Gingival Recession (NA)
- Oral Mucosa Wound Healing After Gingival Recession Treatment in Diabetic Patients. A Clinical Study. (NA)
- Hard Tissue Augmentation With or Without Connective Tissue Graft in Immediate Esthetic Implants (NA)
- Vestibular Incision Subperiosteal Tunnel Access With Fascia Lata Allograft in The Treatment of Gingival Recession (NA)
- Impact of Root Surface Conditioning With Erythritol Air Polishing and Hand Instrumentation on Recession Coverage Using the Modified Tunnel Technique and Subepithelial Connective Tissue Graft. (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- connective tissue graft CI brief — competitive landscape report
- connective tissue graft updates RSS · CI watch RSS
- Abeer hassan sharafuddin portfolio CI