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Comparator QIV
Comparator QIV is a quadrivalent inactivated influenza vaccine that stimulates immune responses against four strains of influenza virus.
Comparator QIV is a quadrivalent inactivated influenza vaccine that stimulates immune responses against four strains of influenza virus. Used for Seasonal influenza prevention in adults and children.
At a glance
| Generic name | Comparator QIV |
|---|---|
| Also known as | Afluria Quadrivalent, Fluarix Quadrivalent |
| Sponsor | Seqirus |
| Drug class | Inactivated influenza vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
QIV vaccines contain inactivated (killed) virus particles or viral antigens from two influenza A strains and two influenza B strains. Upon administration, they trigger both humoral and cellular immune responses, leading to the production of antibodies and T-cell responses that provide protection against infection with the included influenza strains.
Approved indications
- Seasonal influenza prevention in adults and children
Common side effects
- Injection site reactions (pain, redness, swelling)
- Myalgia
- Headache
- Fatigue
- Low-grade fever
Key clinical trials
- Influenza Vaccination Strategy for Patients With Hematologic Malignancy (PHASE3)
- A Study to Evaluate the Safety and Immunogenicity of Two Doses of DCVC H1 HA mRNA-LNP in Healthy Adults (PHASE1)
- A Study to Find the Dose and Assess the Immune Response and Safety of a Vaccine Against Influenza in Healthy Younger and Older Adults (PHASE2)
- A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults (PHASE2)
- A Study to Evaluate the Safety and Immunogenicity of a Single Dose of H1ssF-3928 mRNA-LNP in Healthy Adults (PHASE1)
- A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age (PHASE3)
- Efficacy Study With QIVc in Pediatric Subjects (PHASE3)
- Effect of Oral Supplements for Influenza Vaccine Response (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Comparator QIV CI brief — competitive landscape report
- Comparator QIV updates RSS · CI watch RSS
- Seqirus portfolio CI