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Cocktail of CYP450 substrates
Cocktail of CYP450 substrates is a Small molecule drug developed by Galapagos NV. It is currently in Phase 1 development.
At a glance
| Generic name | Cocktail of CYP450 substrates |
|---|---|
| Sponsor | Galapagos NV |
| Modality | Small molecule |
| Phase | Phase 1 |
Approved indications
Common side effects
- International normalised ratio increased
- Nausea
- Headache
- Abdominal pain
- Constipation
- Vomiting
- Urinary tract infection
- Blood bilirubin increased
- Back pain
- Abdominal pain upper
- Diarrhoea
- Gastrointestinal pain
Key clinical trials
- A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer (PHASE1)
- Effect of Dexamethasone on CYP Enzyme Activity in Healthy Male Subjects (PHASE1)
- Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study (EARLY_PHASE1)
- An Open-label, DDI Study to Investigate the Effects of Amlitelimab on the PK of Selected Cytochrome P450 Substrates (PHASE1)
- Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis (EARLY_PHASE1)
- A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis (NA)
- Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects (PHASE1)
- Interaction of BI 425809 With Midazolam, Warfarin, Omeprazole and Digoxin (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Cocktail of CYP450 substrates CI brief — competitive landscape report
- Cocktail of CYP450 substrates updates RSS · CI watch RSS
- Galapagos NV portfolio CI
Frequently asked questions about Cocktail of CYP450 substrates
What is Cocktail of CYP450 substrates?
Cocktail of CYP450 substrates is a Small molecule drug developed by Galapagos NV.
Who makes Cocktail of CYP450 substrates?
Cocktail of CYP450 substrates is developed by Galapagos NV (see full Galapagos NV pipeline at /company/galapagos-nv).
What development phase is Cocktail of CYP450 substrates in?
Cocktail of CYP450 substrates is in Phase 1.
What are the side effects of Cocktail of CYP450 substrates?
Common side effects of Cocktail of CYP450 substrates include International normalised ratio increased, Nausea, Headache, Abdominal pain, Constipation, Vomiting.
Related
- Manufacturer: Galapagos NV — full pipeline
- Compare: Cocktail of CYP450 substrates vs similar drugs
- Pricing: Cocktail of CYP450 substrates cost, discount & access