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Coated Vicryl plus
Coated Vicryl Plus is an absorbable surgical suture that provides wound closure with antimicrobial properties through an iodine-based coating.
Coated Vicryl Plus is an absorbable surgical suture that provides wound closure with antimicrobial properties through an iodine-based coating. Used for General surgical wound closure, Reduction of surgical site infections in general surgery.
At a glance
| Generic name | Coated Vicryl plus |
|---|---|
| Also known as | Coated Polyglactin 910 with Triclosan |
| Sponsor | ClinAmygate |
| Drug class | Absorbable surgical suture with antimicrobial coating |
| Modality | Small molecule |
| Therapeutic area | Surgery/Wound Care |
| Phase | FDA-approved |
Mechanism of action
Vicryl Plus is a braided, absorbable suture made from a copolymer of polyglactin 910, coated with an antimicrobial agent (iodine complex) to reduce surgical site infections. The suture is gradually absorbed by the body over 56-70 days while maintaining tensile strength during the critical wound healing phase. The antimicrobial coating helps prevent bacterial colonization at the surgical site.
Approved indications
- General surgical wound closure
- Reduction of surgical site infections in general surgery
Common side effects
- Surgical site infection
- Wound dehiscence
- Inflammatory reaction
Key clinical trials
- Antibiotic-coated Braided Suture Study (NA)
- Wound Healing and Bacterial Adherence With Triclosan-Coated Sutures After Mandibular Impacted Third Molar Surgery (NA)
- Purse String Versus Conventional Wound Closure Techniques in Children Undergoing Stoma Reversal (NA)
- Comparison of Self-Locking Versus Traditional Sutures in Double-Layer Laparoscopic Vaginal Vault Closure After Hysterectomy (BI-SURE Trial) (NA)
- Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient (NA)
- Prophylactic Mesh Reinforcement for Stoma Closure (NA)
- Modularities of Management of Severe Grades of Gynecomastia. (NA)
- Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Coated Vicryl plus CI brief — competitive landscape report
- Coated Vicryl plus updates RSS · CI watch RSS
- ClinAmygate portfolio CI