Last reviewed · How we verify

Chlonixin (CLONIXIN)

Phase 2 active Small molecule

Chlonixin (generic name: CLONIXIN) is a clonixin drug. It is currently in Phase 2 development.

Chlonixin works by inhibiting the enzyme dihydroorotate dehydrogenase, which is involved in the production of pyrimidine nucleotides.

Chlonixin, also known as CLONIXIN, is a small molecule drug that targets dihydroorotate dehydrogenase (quinone), a mitochondrial enzyme. It belongs to the clonixin drug class and is used to treat certain conditions. However, its commercial status and approved indications are unknown. Further research is needed to determine its safety profile and potential side effects. As a result, it is not currently available on the market.

Likelihood of approval
15.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameCLONIXIN
Drug classclonixin
TargetDihydroorotate dehydrogenase (quinone), mitochondrial
ModalitySmall molecule
Therapeutic areaOther
PhasePhase 2

Mechanism of action

Think of it like a traffic cop: dihydroorotate dehydrogenase helps control the flow of building blocks for DNA and RNA. Chlonixin acts like a roadblock, preventing this enzyme from doing its job. This can help slow down the growth of cells, which can be beneficial in treating certain conditions.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Chlonixin

What is Chlonixin?

Chlonixin (CLONIXIN) is a clonixin drug.

How does Chlonixin work?

Chlonixin works by inhibiting the enzyme dihydroorotate dehydrogenase, which is involved in the production of pyrimidine nucleotides.

What is the generic name of Chlonixin?

CLONIXIN is the generic (nonproprietary) name of Chlonixin.

What drug class is Chlonixin in?

Chlonixin belongs to the clonixin class. See all clonixin drugs at /class/clonixin.

What development phase is Chlonixin in?

Chlonixin is in Phase 2.

What does Chlonixin target?

Chlonixin targets Dihydroorotate dehydrogenase (quinone), mitochondrial and is a clonixin.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing