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Citramag powder
Citramag powder is a Osmotic laxative Small molecule drug developed by London North West Healthcare NHS Trust. It is currently in Phase 3 development for Bowel cleansing prior to colonoscopy, Bowel cleansing prior to radiological examination, Bowel cleansing prior to surgery.
Citramag is a bowel cleansing agent that works as an osmotic laxative to evacuate the colon before medical procedures.
Citramag powder is a medication used in clinical trials for various conditions, including Small Bowel Disease, Gastrointestinal Hemorrhage, Refractory Anemia, Sleep, and Hypertension. The exact mechanism of Citramag powder is unknown, as per ChEMBL, but it has been studied alongside other interventions such as Senna and Metoclopramide in clinical trials.
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Baseline phase 3 → approval rate
+58.3pp
Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
| Regulator | Country | Likely year | Lag vs FDA |
|---|---|---|---|
| FDA | US | 2028–2030 | — |
| EMA | EU | 2029–2031 | +0.7 yr |
| MHRA | GB | 2029–2031 | +0.7 yr |
| Health Canada | CA | 2029–2032 | +0.9 yr |
| TGA | AU | 2029–2032 | +1.2 yr |
| PMDA | JP | 2029–2032 | +1.5 yr |
| NMPA | CN | 2030–2033 | +2.3 yr |
| MFDS | KR | 2029–2032 | +1.4 yr |
| CDSCO | IN | 2029–2033 | +1.8 yr |
| ANVISA | BR | 2030–2033 | +2.3 yr |
Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).
Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.
At a glance
| Generic name | Citramag powder |
|---|---|
| Sponsor | London North West Healthcare NHS Trust |
| Drug class | Osmotic laxative |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | Phase 3 |
Mechanism of action
Citramag contains magnesium citrate, which acts as an osmotic laxative by drawing water into the intestinal lumen, increasing stool bulk and promoting bowel evacuation. The citrate component provides additional osmotic effect and helps maintain the solution's palatability. It is used to cleanse the bowel prior to colonoscopy, radiological procedures, or surgery.
Approved indications
- Bowel cleansing prior to colonoscopy
- Bowel cleansing prior to radiological examination
- Bowel cleansing prior to surgery
Common side effects
- Nausea
- Abdominal discomfort
- Diarrhea
- Vomiting
Key clinical trials
- Role of Medication in Making Urine Less Acidic as Part of Kidney Stone Prevention (PHASE1)
- Comparing the Bowel Cleansing Efcacy of Picosulfate Sodium/ Citric Acid / Magnesium Oxide and Polyethylene Glycol: A Randomized Trial in Taiwan (NA)
- Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension (PHASE4)
- Study to Assess Impact of Dietary Supplement on Sleep Health (NA)
- Effects of Magnesium Supplementation on Hemodynamic Parameters and Cognitive Function (NA)
- Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients (PHASE1, PHASE2)
- Bioavailability of Magnesium Supplements (NA)
- Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Citramag powder CI brief — competitive landscape report
- Citramag powder updates RSS · CI watch RSS
- London North West Healthcare NHS Trust portfolio CI
Frequently asked questions about Citramag powder
What is Citramag powder?
How does Citramag powder work?
What is Citramag powder used for?
Who makes Citramag powder?
What drug class is Citramag powder in?
What development phase is Citramag powder in?
What are the side effects of Citramag powder?
Related
- Drug class: All Osmotic laxative drugs
- Manufacturer: London North West Healthcare NHS Trust — full pipeline
- Therapeutic area: All drugs in Gastroenterology
- Indication: Drugs for Bowel cleansing prior to colonoscopy
- Indication: Drugs for Bowel cleansing prior to radiological examination
- Indication: Drugs for Bowel cleansing prior to surgery
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing