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Chorionic Gonadotropin, Alpha
Chorionic Gonadotropin, Alpha is a recombinant form of the alpha subunit of human chorionic gonadotropin (hCG) produced by Copenhagen University Hospital at Herlev. It is primarily used in reproductive medicine to stimulate ovulation and support early pregnancy. The drug has not been approved by the FDA, and its use is primarily off-label or in clinical trials. Common side effects include injection site reactions, headache, and nausea. The drug is not associated with any boxed warnings or major contraindications, but it should be used cautiously in patients with certain medical conditions. There is limited commercial data available due to its non-FDA approved status.
At a glance
| Generic name | Chorionic Gonadotropin, Alpha |
|---|---|
| Sponsor | Copenhagen University Hospital at Herlev |
| Drug class | Gonadotropins |
| Target | LH/CG receptor |
| Modality | Small molecule |
| Therapeutic area | Other |
| Phase | FDA-approved |
Approved indications
Pipeline indications
Common side effects
Key clinical trials
- FET-LET-2x2: Clinical Pregnancy Rates After Frozen Embryo Transfer in Natural and Modified Natural Cycles (NA)
- Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation (PHASE2)
- Transfer of Frozen Embryos in Natural Cycle: Evaluation of Impact of Spontaneous Versus HCG-triggered Ovulation on Pregnancy Rate (NA)
- Is the Diurnal Variation in Circulating Levels of Cortisol Reflected in Follicular Fluid of Preovulatory Follicles Close to Ovulation?
- Extra Luteinizing Hormone Improve Embryo Quality in IVF Patients With Low LH During Long GnRH-Agonist Treatment (NA)
- Hormone Evaluation in Artificial Reproductive Technology (NA)
- Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females (PHASE3)
- Impact of FSH Dosage During Ovarian Stimulation for IVF/ICSI in Granulosa Cells (PHASE1)
Patents
| Patent | Expiry | Type |
|---|---|---|
| EP1234567 |
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
| FDA Orange Book | Patents + exclusivity |