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Choline C-11 (CHOLINE C-11)

Mcprf · FDA-approved approved Small molecule Quality 38/100

Choline C-11 works by binding to a specific target in the body, allowing for diagnostic imaging.

At a glance

Generic nameCHOLINE C-11
SponsorMcprf
Drug classRadioactive Diagnostic Agent [EPC]
TargetHigh affinity choline transporter 1
ModalitySmall molecule
Therapeutic areaOncology
PhaseFDA-approved
First approval2012

Mechanism of action

Choline 11 Injection is radiolabeled analog of choline, precursor molecule essential for the biosynthesis of cell membrane phospholipids. Choline is involved in synthesis of the structural components of cell membranes, as well as modulation of trans-membrane signaling. Increased phospholipid synthesis (i.e., increased uptake of choline) has been associated with cell proliferation and the transformation process that occurs in tumor cells.

Approved indications

No approved indications tracked.

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
FDA labelMechanism, indications, dosing, boxed warnings, drug interactions
ClinicalTrials.govTrial enrolment, design, endpoints, results