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Chlorpromazine Pill

Marco G Paggi, MD, PhD · Phase 2 active Small molecule

Chlorpromazine acts as a dopamine antagonist, blocking dopamine receptors in the brain.

Chlorpromazine acts as a dopamine antagonist, blocking dopamine receptors in the brain. Used for Schizophrenia, Acute psychosis.

At a glance

Generic nameChlorpromazine Pill
Also known asTemozolomide
SponsorMarco G Paggi, MD, PhD
Drug classPhenothiazine antipsychotic
TargetDopamine receptor
ModalitySmall molecule
Therapeutic areaPsychiatry
PhasePhase 2

Mechanism of action

This leads to a decrease in the activity of the dopaminergic system, which is involved in the regulation of movement and other functions. Chlorpromazine's mechanism of action is complex and multifaceted, involving the blockade of multiple dopamine receptor subtypes. This results in a range of therapeutic effects, including the reduction of psychotic symptoms and the management of movement disorders.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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