Last reviewed · How we verify
Chloroprocaine HCl 1%
Chloroprocaine HCl 1% is a local anesthetic that works by blocking nerve impulses in the body.
Chloroprocaine HCl 1% is a local anesthetic that works by blocking nerve impulses in the body. Used for Regional anesthesia for surgical procedures.
At a glance
| Generic name | Chloroprocaine HCl 1% |
|---|---|
| Also known as | Ampres 1% |
| Sponsor | Sintetica SA |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 2 |
Mechanism of action
It does this by inhibiting the voltage-gated sodium channels in the neuronal membrane, which prevents the initiation and transmission of nerve impulses. This results in a temporary loss of sensation and motor function in the affected area.
Approved indications
- Regional anesthesia for surgical procedures
Common side effects
- Numbness
- Tingling
- Dizziness
Key clinical trials
- The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population (PHASE2)
- Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric Population (PHASE3)
- Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal Injections (PHASE4)
- Comparing Spinal Anesthesia With 1% Chloroprocaine Versus 1% Mepivacaine in Patients Undergoing Outpatient Primary Total Knee Arthroplasty (PHASE4)
- Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section (NA)
- 1% Chloroprocaine(PF) vs. Bupivacaine Spinals (PHASE2)
- Chloroprocaine Lavage to Improve Outcomes Related to Operative Cesarean Delivery (EARLY_PHASE1)
- Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Chloroprocaine HCl 1% CI brief — competitive landscape report
- Chloroprocaine HCl 1% updates RSS · CI watch RSS
- Sintetica SA portfolio CI