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Chlorhexidine mouth wash
Chlorhexidine mouth wash is a Antimicrobial Small molecule drug developed by Riyadh Colleges of Dentistry and Pharmacy. It is currently in Phase 2 development for Oral infections, Gingivitis, Periodontitis. Also known as: Oraxine 0.2% Chlorhexidine mouth wash.
Binds to bacterial cell walls and membranes, disrupting microbial membrane function and ultimately leading to cell death.
Binds to bacterial cell walls and membranes, disrupting microbial membrane function and ultimately leading to cell death. Used for Oral infections, Gingivitis, Periodontitis.
At a glance
| Generic name | Chlorhexidine mouth wash |
|---|---|
| Also known as | Oraxine 0.2% Chlorhexidine mouth wash |
| Sponsor | Riyadh Colleges of Dentistry and Pharmacy |
| Drug class | Antimicrobial |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | Phase 2 |
Mechanism of action
Chlorhexidine mouthwash exerts its antimicrobial effects by interacting with the negatively charged phosphate groups of bacterial cell membranes, ultimately leading to cell lysis and death.
Approved indications
- Oral infections
- Gingivitis
- Periodontitis
Common side effects
- Gingivitis
- Dental caries
- Oral mucositis
Key clinical trials
- Hyaluronic Gel vs Chlorhexidine in Periodontal Patients (NA)
- PMPR and Chlorhexidine on Periodontal Disease and Vascular Function (NA)
- Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients (NA)
- Microbiological Effect of 0.12% Chlorhexidine Digluconate and 0.05% Cetylpyridinium Chloride vs Probiotics (Lactobacillus Reuteri Prodentis) on Porphyromonas Gingivalis. (PHASE4)
- To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse. (NA)
- Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash (EARLY_PHASE1)
- Clinical Investigation of PerioGard (Test) Regimen (PHASE3)
- Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Chlorhexidine mouth wash CI brief — competitive landscape report
- Chlorhexidine mouth wash updates RSS · CI watch RSS
- Riyadh Colleges of Dentistry and Pharmacy portfolio CI
Frequently asked questions about Chlorhexidine mouth wash
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Related
- Drug class: All Antimicrobial drugs
- Manufacturer: Riyadh Colleges of Dentistry and Pharmacy — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Oral infections
- Indication: Drugs for Gingivitis
- Indication: Drugs for Periodontitis
- Also known as: Oraxine 0.2% Chlorhexidine mouth wash
- Compare: Chlorhexidine mouth wash vs similar drugs
- Pricing: Chlorhexidine mouth wash cost, discount & access