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Chlorhexidine-Alcohol
Chlorhexidine-Alcohol is a Topical antiseptic Small molecule drug developed by Poitiers University Hospital. It is currently FDA-approved for Skin antisepsis and disinfection prior to surgical procedures, Skin preparation for injections and venipuncture, Wound cleansing and disinfection. Also known as: Chloraprep, ChloraPrep, Cardinal Health, Chlorohexidine Gluconate (CHG).
Chlorhexidine-alcohol is a topical antiseptic combination that kills microorganisms through dual antimicrobial action.
Chlorhexidine-Alcohol is a small molecule intervention used in various clinical trials, including studies on Type 1 diabetes, Peripheral Venous Cannulation, Pediatric Cancer, and Chronic Periodontitis.
At a glance
| Generic name | Chlorhexidine-Alcohol |
|---|---|
| Also known as | Chloraprep, ChloraPrep, Cardinal Health, Chlorohexidine Gluconate (CHG) |
| Sponsor | Poitiers University Hospital |
| Drug class | Topical antiseptic |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention / Dermatology |
| Phase | FDA-approved |
Mechanism of action
Chlorhexidine is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, while alcohol (typically ethanol or isopropanol) provides rapid antimicrobial activity and enhances penetration. The combination is commonly used for skin antisepsis and disinfection prior to medical procedures.
Approved indications
- Skin antisepsis and disinfection prior to surgical procedures
- Skin preparation for injections and venipuncture
- Wound cleansing and disinfection
Common side effects
- Skin irritation or erythema
- Contact dermatitis
- Allergic reaction (rare)
Key clinical trials
- Antiplaque Efficacy and Patient Reported Outcome of Chlorohexidine, Cetylpyridinium Chloride, and Essential Oil Mouthwashes in Orthodontic Patients (NA)
- Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy (NA)
- CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee (NA)
- Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (PHASE2)
- Chlorhexidine Gluconate and Alcohol Hand Rubbing on Healthcare-associated Infection (NA)
- The Clinical Role of Anogenital Distance (NA)
- Effectiveness of Screening and Decolonization of S. Aureus to Prevent S. Aureus Surgical Site Infections in Surgery Outpatients
- Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Chlorhexidine-Alcohol CI brief — competitive landscape report
- Chlorhexidine-Alcohol updates RSS · CI watch RSS
- Poitiers University Hospital portfolio CI
Frequently asked questions about Chlorhexidine-Alcohol
What is Chlorhexidine-Alcohol?
How does Chlorhexidine-Alcohol work?
What is Chlorhexidine-Alcohol used for?
Who makes Chlorhexidine-Alcohol?
Is Chlorhexidine-Alcohol also known as anything else?
What drug class is Chlorhexidine-Alcohol in?
What development phase is Chlorhexidine-Alcohol in?
What are the side effects of Chlorhexidine-Alcohol?
Related
- Drug class: All Topical antiseptic drugs
- Manufacturer: Poitiers University Hospital — full pipeline
- Therapeutic area: All drugs in Infection Prevention / Dermatology
- Indication: Drugs for Skin antisepsis and disinfection prior to surgical procedures
- Indication: Drugs for Skin preparation for injections and venipuncture
- Indication: Drugs for Wound cleansing and disinfection
- Also known as: Chloraprep, ChloraPrep, Cardinal Health, Chlorohexidine Gluconate (CHG)
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing