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Nycoton (CHLORAL HYDRATE)
Nycoton works by acting as a central nervous system depressant, slowing down brain activity to induce sleep or anesthesia.
Nycoton, also known as chloral hydrate, is a small molecule drug in the chloral hydrate class. It was originally developed by an unknown entity and its current owner is also unknown. Nycoton is used to treat general anesthesia and insomnia. The commercial status of Nycoton is unclear, but it is likely off-patent. Key safety considerations include its potential for dependence and abuse.
At a glance
| Generic name | CHLORAL HYDRATE |
|---|---|
| Drug class | chloral hydrate |
| Modality | Small molecule |
| Therapeutic area | Neuroscience |
| Phase | discontinued |
Mechanism of action
Imagine your brain is a busy city with lots of activity. Nycoton is like a traffic controller that slows down the flow of traffic, making it easier to fall asleep or relax. This is because it affects the way brain cells communicate with each other, leading to a decrease in activity and a sense of calm.
Approved indications
- General anesthesia
- Insomnia
Common side effects
- Hypomania
- Jaundice cholestatic
- Schizophrenia
- Psychotic disorder
- Cholelithiasis
- Hepatotoxicity
- Blood bilirubin increased
- Total lung capacity increased
- Hepatic enzyme increased
- Asthma-chronic obstructive pulmonary disease overlap syndrome
- Nasal polyps
- Sarcoidosis
Drug interactions
- erythromycin
Key clinical trials
- WASPE Sleep Adjustment for Children Aged 0-4 Years Undergoing Radiation Therapy (NA)
- A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI (NA)
- An Open-label Trial to Evaluate the Safety and Efficacy of Chloral Hydrate in Patients with Severe Insomnia (PHASE4)
- Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children (NA)
- Buccal Midazolam Versus Intranasal Dexmedetomidine Plus Oral Chloral Hydrate in Inguinal Hernia Repair (NA)
- Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural Sedation (NA)
- PANDA (Pediatric Anesthesia & NeuroDevelopment Assessment) Study
- Sedation and Nursing Management in EEG Recording in Children (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Nycoton CI brief — competitive landscape report
- Nycoton updates RSS · CI watch RSS