Last reviewed · How we verify
DEXMEDETOMIDINE
DEXMEDETOMIDINE is a drug. It is currently FDA-approved (first approved 1999).
At a glance
| Generic name | DEXMEDETOMIDINE |
|---|---|
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 1999 |
Approved indications
Common side effects
- Hypotension
- Bradycardia
- Hypertension
- Nausea
- Dry Mouth
- Vomiting
- Atrial Fibrillation
- Fever
- Hypoxia
- Tachycardia
- Anemia
- Hemorrhage
Serious adverse events
- Hypotension Requiring Intervention
- Bradycardia Requiring Intervention
- Ventricular Tachycardia
- Pulmonary Edema
- Atelectasis
- Hypovolemia
- Post-procedural Hemorrhage
- Wheezing
- Hypocalcemia
- Urine Output Decreased
Key clinical trials
- Effect of Lidocaine Infusion Versus Dexmedemidine Infusion on the Neurocognitive Function of Elderly Patients Undergoing Endoscopic Retrograde Cholangiopancreatography(ERCP): a Randomized, Controlled Trial. (NA)
- The Relationship Between Opioid-Free Anesthesia and Postoperative Agitation-Delirium and Quality of Recovery in Pediatric Ear, Nose, and Throat Cases Monitored With Perioperative Bispectral Index
- Continuous Epidural With Dexmedetomidine Adjuvant in Gynecologic Laparotomy (PHASE4)
- Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome (PHASE4)
- Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine (PHASE4)
- Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial (PHASE4)
- Dexmedetomidine for Invasive Ventilation In the NEOnate (PHASE2, PHASE3)
- Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DEXMEDETOMIDINE CI brief — competitive landscape report
- DEXMEDETOMIDINE updates RSS · CI watch RSS
Frequently asked questions about DEXMEDETOMIDINE
What is DEXMEDETOMIDINE?
DEXMEDETOMIDINE is a Small molecule drug.
When was DEXMEDETOMIDINE approved?
DEXMEDETOMIDINE was first approved on 1999.
What development phase is DEXMEDETOMIDINE in?
DEXMEDETOMIDINE is FDA-approved (marketed).
What are the side effects of DEXMEDETOMIDINE?
Common side effects of DEXMEDETOMIDINE include Hypotension, Bradycardia, Hypertension, Nausea, Dry Mouth, Vomiting. Serious adverse events: Hypotension Requiring Intervention, Bradycardia Requiring Intervention, Ventricular Tachycardia, Pulmonary Edema.
Related
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing