Last reviewed · How we verify
FUROSEMIDE
FUROSEMIDE is a Loop Diuretic [EPC] drug. It is currently FDA-approved (first approved 1966).
At a glance
| Generic name | FUROSEMIDE |
|---|---|
| Drug class | Loop Diuretic [EPC] |
| Modality | Small molecule |
| Phase | FDA-approved |
| First approval | 1966 |
Approved indications
Common side effects
- anorexia
- oral and gastric irritation
- cramping
- diarrhea
- constipation
- nausea
- vomiting
- severe anaphylactic or anaphylactoid reactions
- systemic vasculitis
- interstitial nephritis
- necrotizing angiitis
- tinnitus and hearing loss
Key clinical trials
- Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib (PHASE1)
- A Clinical Study of the Effect of MK-2828 on Rosuvastatin or Furosemide in Healthy People (MK-2828-005) (PHASE1)
- A Protocol Based-Furosemide Stress Test to Evaluate Renal Recovery During Continuous Renal Replacement Therapy (PHASE4)
- Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study (PHASE4)
- POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart Failure (PHASE2, PHASE3)
- Study to Compare Bioavailability and Pharmacokinetics of a Novel Furosemide Regimen Administered Subcutaneously Versus the Same Dose (80 mg) Administered Intravenously in Healthy Volunteers (PHASE1)
- Empagliflozin in Acute Heart Failure (PHASE4)
- Comparison of the Effectiveness of Different Diuretic Therapies in the Management of Acute Heart Failure (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- FUROSEMIDE CI brief — competitive landscape report
- FUROSEMIDE updates RSS · CI watch RSS
Frequently asked questions about FUROSEMIDE
What is FUROSEMIDE?
FUROSEMIDE is a Loop Diuretic [EPC] drug.
What drug class is FUROSEMIDE in?
FUROSEMIDE belongs to the Loop Diuretic [EPC] class. See all Loop Diuretic [EPC] drugs at /class/loop-diuretic-epc.
When was FUROSEMIDE approved?
FUROSEMIDE was first approved on 1966.
What development phase is FUROSEMIDE in?
FUROSEMIDE is FDA-approved (marketed).
What are the side effects of FUROSEMIDE?
Common side effects of FUROSEMIDE include anorexia, oral and gastric irritation, cramping, diarrhea, constipation, nausea.
Related
- Drug class: All Loop Diuretic [EPC] drugs
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing